The FLT1-201 isoform exhibits alternative splicing at exon 12, resulting in a shorter transcript, while FLT1-203 deviates from FLT1-001 at an alternatively spliced exon 15a to form a 733aa soluble Flt1 (sFlt1-e15a) isoform identified in a previous study [31] which is significantly upregulated in preeclampsia [37,38]. The gene discussed is FLT1; the disease is preeclampsia.