In fact, there are many studies on autoimmune and endotoxin-induced uveitis (EIU) animal models, as well as studies on aqueous, vitreous and serum of patients with uveitis, which show a central role of Th17 cells and related pro-inflammatory cytokines such as interleukin 6 (IL-6), interleukin 10 (IL-10), interleukin 17 (IL-17), interleukin 22 (IL-22), interleukin 23 (IL-23) and TNF-α in the pathogenesis of uveitis itself [11]. The gene discussed is IL37; the disease is uveitis.