Mertoglu et al. [42] found that serum creatinine and BUN have greater diagnostic value compared with other novel markers including myo-inositol oxygenase and cystatin C. Laranja et al. [4] revealed that septic patients with AKI had lower urine output compared with patients with AKI from other cases or chronic kidney disease. The gene discussed is MIOX; the disease is chronic kidney disease.