Meanwhile, in another large, prospective, population-based cohort, including 5476 male and female participants in the Netherlands, alcohol consumption was inversely associated with the risk of developing CKD, defined as either an eGFR < 60 mL/min/1.73 m2 or proteinuria (24-h urinary albumin excretion > 30 mg) [12]. This evidence concerns the gene ALB and chronic kidney disease.