Using univariate Cox analysis, we found the expressions of BAK1, CYCS, CHMP4A, NLRP6, NLRC4, NOD2, GPX4, GSDMD, GSDMC, TP53, and IL18 were related to the prognosis of HCC with P < 0.20 in the TCGA cohort (Fig. 3A). The gene discussed is IL18; the disease is hepatocellular carcinoma.