Notably, the size of the MAIT cell compartment in HD at day 0 and day 35 correlated positively with the spike-specific CD4 T cell response at day 35 as determined by Spearman’s rank correlation test (r = 0.46, p = 0.002, and r = 0.47, p = 0.002, respectively) (Fig. 1E, F). The gene discussed is CD4; the disease is Huntington disease.