With regards to the HPV-associated HNSCC, HOXB13, HOXC5, HOXC6, HOXC9, and HOXD11 were differentially expressed between HPV-positive and HPV-negative HNSCC (p < 0.05, Supplementary Table S5). The gene discussed is HOXC6; the disease is head and neck squamous cell carcinoma.