Similarly, KC/Pd mice fed the HFD had significantly higher production of 3 chemokines (Ccl2 and Ccl4-5) than did KC/Pd mice on the control diet, while KC mice fed the HFD had higher Ccl2 and Ccl20 production than did KC mice on the control diet (Fig. 6a, c, Supplementary Fig. 7j–l). Here, CCL20 is linked to keratoconus.