KC/Pd mice fed the GW diet for 3 and 9 days had significantly higher production of 5 chemokines (Ccl2, Ccl4-5, Ccl11, and Cxcl1) and 8 chemokines (Ccl2-4, Ccl11, Ccl17, Ccl20, Cxcl1, and Cxcl5), respectively, compared to KC/Pd mice on the control diet (GW diet for 0 days) or to KC mice on the same treatment (Fig. 6a, b, Supplementary Fig. 7a–i). This evidence concerns the gene CCL2 and keratoconus.