The screen results revealed increases in 5 of 13 screened cytokines (Il6, Tnfa, Csf2, Il1a, and Ccl2) at 3 days and 9 days of the GW treatment in KC/Pd mice compared to KC mice on the same treatment or to KC/Pd mice on the control diet (GW for 0 days) (Fig. 5p, Supplementary Fig. 6g–k). Here, CSF2 is linked to keratoconus.