Notably, besides the release of several DAMPs from dying cancer cells (e.g., ATP, HMGB1, CRT, ERp57, HSP90 and vasostatin) the suppression of CD47 (the “don’t eat me” signal) and up-regulation of inflammatory chemokines (CXCL1–3, 10, 12 and 13) have also been observed [143]. This evidence concerns the gene HMGB1 and cancer.