Furthermore, receiver operating characteristic (ROC) analysis showed that combined use of DMDRMR, miR-378a-5p and DAB2IP expression could improve the area under curve (AUC) value for the diagnosis of ccRCC (Fig. 8H), suggesting that the combination of DMDRMR, miR-378a-5p and DAB2IP expression can serve as a diagnostic biomarker of ccRCC. Here, DAB2IP is linked to nonpapillary renal cell carcinoma.