As an indication of disease severity, we measured the mRNA expression levels of IFN-stimulated genes (IFIT1, IFIT3, ISG15, and MX2), pro-inflammatory cytokines (IL6, IL10), and chemokines (CXCL10, CCL2) that are correlated with COVID-19 exacerbation. The gene discussed is IFIT1; the disease is COVID-19.