The transcriptome data show that Col6a1, Col6a2, and Col6a3 had more expression in both MuPαC and SMPαC compared to SMC and ICC (S4 Table), suggesting that COL6A1-3 are mainly expressed in colonic PαC (SMPαC and MuPαC). This evidence concerns the gene COL6A3 and intrahepatic cholangiocarcinoma.