The estimated cumulative effect of all variants associated with T2D (CAPN1043, CAPN1063, ABCC8, KCNJ11, CTF7L2A, CTF7L2B and PPARG), revealed mean risk scores for ranging from 0.484 in the Arara group to 0.620 in the Xikrin do Bacajá group. The gene discussed is KCNJ11; the disease is type 2 diabetes mellitus.