The estimated cumulative effect of all variants associated with T2D (CAPN1043, CAPN1063, ABCC8, KCNJ11, CTF7L2A, CTF7L2B and PPARG), revealed mean risk scores for ranging from 0.484 in the Arara group to 0.620 in the Xikrin do Bacajá group. This evidence concerns the gene ABCC8 and type 2 diabetes mellitus.