Studies have shown that variants in KCNJ11 are associated with T2D in Europeans in the United Kingdom (Gloyn et al., 2003), and variants in ABCC8 have been correlated with T2D in Japanese populations (Sakamoto et al., 2007), Caucasians (Florez et al., 2004) and Chinese (Zhou et al., 2019). This evidence concerns the gene KCNJ11 and type 2 diabetes mellitus.