We applied summary statistics from GWAS of depression [56], CAD [40], body mass index (BMI) [57], systolic blood pressure (SBP) [42], diastolic blood pressure (DBP) [42], high-density lipoprotein (HDL) [58], low-density lipoprotein (LDL) [58], triglycerides (TG) [58], total cholesterol (TC) [58], (T2D) [59], c-reactive protein (CRP) [60]. The gene discussed is CRP; the disease is depressive symptom measurement.