With the aim to corroborate our results in CRC (Fiore et al., 2019) and extend the study to other modified adenosines and investigate if FBXW7 modulation is a common mechanism in other cancer systems, we evaluated IPA and N6-BA effects in GBM models (U87, U251 and T98) exhibiting different FBXW7 basal levels. Here, CFB is linked to glioblastoma.