ZAG, a lipid mobilizing factor, is a novel adipokine, which may be involved in the local regulation of adipose tissue function.53 ZAG is overexpressed in malignant tumors such that it may serve as a liver cancer marker.54 ZAG is actively involved in both inhibition of tumor growth and proliferation,55 inhibit the enzyme mediated tumor invasion and activate apoptosis.56 The high expression of ZAG in M group might indicate functional maintenance. This evidence concerns the gene AZGP1 and neoplasm.