The severe OSA-related m6A regulators were obtained by the results of two algorithms overlapped (Figure 3D), and finally seven m6A regulators remained, including HNRNPA2B1, METTL3, KIAA1429, YTHDF2, FMR1, IGF2BP1 and IGF2BP3. This evidence concerns the gene IGF2BP3 and obstructive sleep apnea syndrome.