Since the accumulation of TILs and immunomodulators expression in PCa was associated with patient prognosis, TK1 may be involved in immune tolerance via interacting with TILs and immunomodulatory molecules, and can be used as a potential marker for prostate immunotherapy (Steele et al., 2018; Pérez-Ruiz et al., 2020; Yang et al., 2021). The gene discussed is TK1; the disease is posterior cortical atrophy.