MMP14 and glioblastoma: MT1-MMP expression was increased in ConA-activated glioblastoma cells, and the expression of autophagy-related markers Bcl-2, ATG9, and LC3 was also enhanced, with autophagosome formation; after silencing of the MT1-MMP genes by SiRNA, the expression of these genes was decreased and autophagy was inhibited (Pratt et al., 2012; Pratt et al., 2016; Desjarlais and Annabi, 2019).