Qin et al. found that the adding of IL-6 to starvation-induced lymphoma U937 cells significantly increased the phosphorylation level of STAT3, while the level of autophagy was significantly downregulated, suggesting that IL-6 inhibits cellular autophagy through activation of the STAT3 signaling pathway (Qin et al., 2022). The gene discussed is STAT3; the disease is lymphoma.