STAT3 and gallbladder cancer: According to Yang, under glucose-deficient conditions in vitro and in vivo, the kinase activator MOB1A, which plays an important role in many diseases and cancers, plays a key role in the development of gallbladder cancer (GBC) by promoting autophagy through activation of the IL6/STAT3 signaling pathway and modulation of gemcitabine chemosensitivity (Yang et al., 2020).