Pratt et al. found in glioblastoma U87 cells that ConA induced overexpression of MT1-MMP gene and protein, followed by increased STAT3 phosphorylation, which finally led to increased autophagy (upregulated expressions of biomarker BNIP3 gene and protein) (Pratt and Annabi, 2014). This evidence concerns the gene MMP14 and glioblastoma.