The A cluster was characterized by eosinophilia, the C cluster was characterized by effector memory CD4+/CD8+ T cells, activated CD4+/CD8+ T cells, activated B cells, activated dendritic cells, immature B cells, immature dendritic cells, MDSC, regulatory T cells, T follicular helper cells, and type 17 T helper cells. The gene discussed is CD8A; the disease is Increased total eosinophil count.