In addition, these six sites all had a significantly lower editing level in sepsis than in controls: HAUS2:chr15:42567145 (p = 0.0081), PPP3CB:chr10:73450485 (p = 0.045), HOOK3:chr8:43028233 (p = 0.023), CSMD1:chr8:4877650 (p = 0.043), METTL7A:chr12:50930723 (p = 0.0049), and KLC2:chr11:66261078 (p = 0.047) (Supplementary Figures S3A–F). The gene discussed is HOOK3; the disease is Sepsis.