The results also showed that protein phosphatase 3 catalytic subunit beta (PPP3CB), kinesin light chain 2 (KLC2), proteasome 20S subunit beta 2 (PSMB2), and Matrin 3 (MATR3) were associated with amyotrophic lateral sclerosis, and PPP3CB, KLC2, and PSMB2 were associated with prion disease, Alzheimer’s disease, and pathways of neurodegeneration (Supplementary Table S6), pointing to the association of sepsis with neurological damage and the important role of A-to-I RNA editing in it. The gene discussed is MATR3; the disease is Sepsis.