These results are in agreement with previous reports indicating similar associations between PRAL as well as NEAP and the prevalence of MetS in Iranian patients with type 2 diabetes (40) and a cross-sectional Japanese study, in which higher NEAP values (PRAL was not calculated) were associated with an increased prevalence of MetS independently of sex, age, and BMI (17). The gene discussed is PRAL; the disease is metabolic syndrome.