In addition, under acarbose and metformin treatment, significant and comparable effects on reduction of BMI and HbA1c were still achieved, while under acarbose treatment, significantly lower postprandial blood glucose was achieved after 48 weeks, and AUC for serum insulin decreased to a greater extent than under metformin treatment, demonstrating that acarbose is superior to metformin in reducing postprandial hyperglycemia and hyperinsulinemia in patients with T2DM consuming an Asian diet. This evidence concerns the gene INS and Hyperglycemia.