In addition, TMPRSS2 is also expressed in the aerodigestive tract, facilitating the entry of coronavirus particles into cells by cleaving the spike protein and making people more susceptible to infection of SARS-CoV-2 (Hoffmann et al., 2020; Walls et al., 2020; Wrapp et al., 2020). The gene discussed is TMPRSS2; the disease is infection.