Compared with the normal tissues, the expression of TMPRSS2 was higher in ESCA (esophageal carcinoma), KIRP (kidney renal papillary cell carcinoma), LUAD (lung adenocarcinoma), READ (rectum adenocarcinoma), and UCEC (uterine corpus endometrial carcinoma) (Figure 1B). This evidence concerns the gene TMPRSS2 and rectum adenocarcinoma.