Baseline tumor biopsies indicated responders had higher infiltration of T lymphocytes and a higher percentage of PD-L1+ macrophages, as well as effector memory and regulatory T cells.14 Petitprez et al. carried out analyses across a number of STS cohorts, identifying five sarcoma immune classes with histological subtypes evenly distributed across the most immune-rich classes. This evidence concerns the gene CD274 and sarcoma.