KDM4B and gastric adenocarcinoma: When exposed to hypoxia and radiation, histone H3 methylation of gastric adenocarcinoma cells was in a state of dynamic transformation, and JMJD2B-mediated modification mechanisms function to enhance the expression of cyclin A1 (CCNA1) and further facilitate the growth of gastric adenocarcinoma cells under hypoxia and radiation stress (67).