Our results revealed that in GBM cancer cells, expression of CD274 (PD-L1), PDCD1LG2 (PD-L2), LGALS9 (Galectin-9), and PVR (CD155) were positively correlated with the expression of multiple m6A regulators, especially YTHDF2, YTHDF3, LRPPRC, METTL3, RBM15B, FTO, and ALKBH5 (Supplementary Figures 11A, B). This evidence concerns the gene METTL3 and cancer.