TGFB1 and neoplasm: Sørensen et al. (23) reported interesting phenomenon that on average 44% and 8% of the tumor associated macrophages (TAM) expressed the marker HLA-DR and TNF-α for M1 macrophages, respectively, while 10% and 3% of TAMs expressed IL10 and TGF-β1, which were markers for M2 macrophages.