HLA types - HLA-DRB1*11:01skin and HLA-DQB1*03:01GI alleles (113)Predominance of HLA-DR4 (114)HLA-DR15, B52 and Cw12 irAE-pitutary (115).HLA-DRB1*04: 05 for irAE-arthritis (116)HLA-DPA1*02:02 and DPB1*05:01 in irAE-diabetes (117). This evidence concerns the gene HLA-DRB1 and arthritic joint disease.