MTOR and posterior cortical atrophy: We thus investigated the protein level of PKM2 in the MALAT1/MYBL2/mTOR axis and found that silencing MALAT1, MYBL2, or inhibited mTOR by using rapamycin decreases the expression of PKM2 in PCa cell lines, and the addition of the mTOR pathway activator could reverse this phenomenon (Figures 4(h) and S2D).