Conditional PC-specific Scn8a knockout mice were previously found to exhibit ataxia, impaired coordination, and deficits in delay eyeblink conditioning and Morris water maze tests (Levin et al., 2006; Woodruff-Pak et al., 2006) which are frequently observed in animal models with autistic features (Tsai et al., 2012; Reith et al., 2013; Piochon et al., 2014; Kloth et al., 2015; Cupolillo et al., 2016). The gene discussed is SCN8A; the disease is cerebellar ataxia.