KIT and diabetes mellitus: In a murine model of wound healing, recruitment of BM-derived cells was impaired by experimental T1D-like streptozotocin (STZ)-induced diabetes.27 Similarly, recruitment of BM-derived cells to areas of carotid endothelial damage, including murine HSPCs (LKS cells, Lin-Sca1+c-Kit+), was impaired in STZ diabetes.28 These data provide no support to the hypothesis that HSPCs are “wasted” in an attempt to repair ongoing tissue damage.