CXCL13 was secreted by PD-1hiCD8+ T cells in lung cancer (30), by CD103+CD8+ cells in ovarian cancer (31), and by CXCR5–PD-1hiCD4+ follicular helper like T cells in breast cancer (32) and nasopharyngeal cancer (33). This evidence concerns the gene CXCR5 and lung carcinoma.