CXCL12 neutralization abolished the 7HP349 treatment–related increase in frequencies of CD8+ and CD4+ Teffs (Figure 8C) and tumor myeloid cell infiltrates consisting of IMs, granulocytes, M1 macrophages, M2 macrophages, pDC, and cDC2 (Figure 8D). Here, CXCL12 is linked to neoplasm.