KMT2A and acute myeloid leukemia: Furthermore, AML cases with rare complex I variants were likely to have a higher white cell count (P = 0.06), higher bone marrow blast percentage (P < 10−6), less likely to have French–American–British morphology M2 (P = 0.003) and more likely to have a mixed-lineage leukaemia (MLL/KMT2A) gene rearrangement (P = 0.003) (Supplementary Data 4).