To determine the OXPHOS capacity of primary AML specimens with rare complex I variants, IDH1- or IDH2-mutant samples, and WT primary AML samples (without complex I variants, IDH1- or IDH2-mutation), we measured mitochondrial copy number and OCR in bone marrow mononuclear cells from AML specimens (Supplementary Data 5). Here, IDH1 is linked to acute myeloid leukemia.