NALCN and Hypotonia: The mutations in the NALCN gene lead to genetic diseases such as Infantile Hypotonia with Psychomotor Retardation and Characteristic Facies 1 (IHPRF1; OMIM 615419)3,4 and Congenital Contractures of the Limbs and Face, Hypotonia, and Developmental Delay (CLIFAHDD; OMIM 616266)5.