HAVCR2 and spontaneous abortion: The number and function of Tim-3+dMφs in the decidua were significantly impaired in miscarriage, and adoptive transfer of Tim-3+Mφs, not Tim-3−Mφs relieved murine embryo absorption induced by Mφ depletion also suggesting that the expression of Tim-3 on dMφs during pregnancy might conduce to the maintenance of maternal-fetal immune tolerance and normal pregnancy.