For instance, circ_0016760 accelerates NSCLC progression by modulating G antigen 1 and is linked to the adverse prognosis of the patients [22]; circ-PRMT5 overexpression can facilitate enhancer of zeste homolog 2 expressions to promote the proliferation of NSCLC cells [23]; circ_0078767 accelerates cancer development by maintaining Ras association domain family member 1 expression in NSCLC [24]. This evidence concerns the gene PRMT5 and cancer.