Transcriptional profiling of ERG knockdown in the TMPPRSS2: ERG-positive PCa cell line VCaP (VCaP-siERG) has shown 265 and 291 features that are over and underexpressed, respectively, in VCaP-siERG relative to VCaP treated with nontargeting siRNA [41]. Here, ERG is linked to posterior cortical atrophy.