In this regard, some authors have advised that hyperglycemia following a high glycemic index diet and subsequent compensatory hyperinsulinemia may stimulate the release of autonomic counter-regulatory hormones (e.g., cortisol, adrenaline, growth hormone, glucagon), which could exert an impact on sleep disturbances (Gais et al., 2003; Gangwisch et al., 2020). The gene discussed is GH1; the disease is Hyperinsulinemia.