TGFB1 and myeloid sarcoma: It was reported that the expression of miR-27a is upregulated, while miR-214 expression is downregulated in relapsing-phase MS patients; the two miRNAs play inhibitory and promoting roles in Th17 differentiation by modulating TGF-β and mTOR signaling, respectively (Ahmadian-Elmi et al., 2016).