Correale et al. suggested the induction of CD8 + CD25 + Foxp3 + cells, CD4+ self-reactive cells, IFN-γ, and IL-17 in the culture plate was inhibited, and the clone of CD8+ regulatory T lymphocytes in the blood and CSF of MS patients in the exacerbation stage is significantly lower than that of patients in the remission stage, indicating that CD8+ regulatory T lymphocytes play a significant regulatory role in MS and may stop the progression of MS (Correale and Villa, 2010). Here, CD4 is linked to myeloid sarcoma.