Among MetS components, after adjusting for age, sex, BMI, CRP, smoking, alcohol drinking, duration of diabetes, hypertension, and history of CVD (model 2), overweight/obesity (BMI ≥ 25 kg/m2) were found to be negatively associated with N-MID (OR = 0.96; 95% CI = 0.94–0.99; P = 0.015) and β-CTX (OR = 0.446; 95% CI = 0.24–0.85; P = 0.014). This evidence concerns the gene CRP and Obesity.