ACTC1 and myocardial infarction: Interestingly, it was observed that endothelial cells are also able to switch on cardiomyocyte lineage genes such as MYL2, myoglobin (MB), MYL3, TNNT2, TNNI3, and ACTC1 following myocardial infarction, indicating the utility of transcriptional profiling and cell marker analysis in detecting cell type shifts, thus facilitating understanding of pathology, e.g., a cell type shift from endothelial cell phenotype to cardiomyocyte phenotype following myocardial infarction (67).