CAT and type 2 diabetes mellitus: Consequently, Ad.CAT gene transfection eliminated T2DM-elevated cytosolic H2O2 levels in CVP neurons (60.6 ± 1.1 in the T2DM+Ad.CAT group vs. 195.8 ± 1.2 in the T2DM group, P < 0.05, Figure 1).