ITGAM and neoplasm: We then examined the tumor-infiltrating cells in the TME and found that with both combination therapy and WGP single therapy, the infiltration of DCs (CD11c+/CD8+) and macrophages (CD11b+/F4-80+) was significantly increased, whereas the frequency of MDSCs (CD11b+/Gr-1+) was significantly decreased (Figure 2A).