TRPC1 and neoplasm: After analysis, the TRPC1 IHC score was increased in the tumor tissue compared with the adjacent tissue (5 ± 2.9 vs. 2.9 ± 1.9, P < 0.001) (Figure 1B); TRPC1 mRNA expression was higher in the tumor tissue than in the adjacent tissue (2.642 (1.652–3.367) vs. 1 (0.643–1.347), P < 0.001) (Figure 1C).