The expression levels of NFS1, CARTPT, APH1B, NDUFA10, and MRPL53 in the hippocampus of CCI with memory impairment model rats 21 days were all significantly downregulated compared to the sham groups (Figure 2A), while ATF3, CBLN1, MT1, and OXTR were all considerably upregulated (Figure 2B), which is consistent with the RNA-Seq expression profiles. This evidence concerns the gene ATF3 and memory impairment.