11 DEmRNAs (APOC1, TMEM106A, TSC22D4, CYR61, BCL6B, MRVI1, LAMC3, BAIAP3, CTXN3, TPBG, and C4B) and 24 DEmRNAs (ABHD10, ARC, CARTPT, CD3E, CLCF1, KIF14, OXTR, RARRES1, SLC18A1, and SLC2A9, etc.)of CCI with memory impairment model rats overlapped with AD and HD model, respectively. This evidence concerns the gene CCN1 and Alzheimer disease.