CD4 and neoplasm: Moreover, immunofluorescence staining results from E.G7-OVA lymphoma model showed that mice treated with combined DCs vaccines, especially E# and F#, displayed an increased infiltration of activated (CD86+, pink signal) B cells (B220+, red signal) and DCs (CD11c+, green signal) in the LN (Figure 5I), as well as an improved recruitment of functional (IFN-γ+, pink signal) CD4+ (red signal) T cells and CD8+ (green signal) T cells in the orthotopic tumor (Figure 5J).