MAPT and Alzheimer disease: Plasma Tau, Aβ40, and Aβ42, and the cortical thickness of each cluster with statistical difference in the AD-NC groups and AD-aMCI groups were subjected to multivariate ordered logistic analysis, and the results were as follows: ordered logistic regression in line with the proportional odds assumption was applied to analyze the influence of plasma Tau, Aβ40, and Aβ42 and the cortical thickness of each cluster on the severity of the patients’ disease.