CLOCK and colorectal cancer: To further illustrate the potential impact of circadian disruption on neurodegeneration-related genes, we analysed the expression profile of the dopaminergic receptor DRD1 (Dopamine Receptor D1) and Huntingtin (HTT) upon perturbation of core clock genes using a recently published transcriptomics time series RNAseq data (ArrayExpress: E-MTAB-9701; (Yalçin et al., 2020)) obtained from HCT116 wild type and core-clock KO human colorectal cancer cells.