Qi et al. studied the biological behavior characteristics and patient survival rate of gastrointestinal stromal tumor (GIST) with PDGFRA mutation, clarified the efficacy of imatinib treatment, and also studied the relationship between gene mutation and gist biological behavior, patient prognosis, and imatinib treatment effect [6]. The gene discussed is PDGFRA; the disease is gastrointestinal stromal tumor.